Download E-books Chemokine Receptors and NeuroAIDS: Beyond Co-Receptor Function and Links to Other Neuropathologies PDF

By Olimpia Meucci (auth.), Olimpia Meucci (eds.)

Chemokines and their receptors are being famous as an crucial element of the worried approach implicated in basic features of improvement and homeostasis, comparable to neurotransmission, proliferation, differentiation, and neuronal-glial communique. therefore, their involvement in HIV neuropathology is going some distance past the co-receptors function and includes complicated interactions of the chemokine approach with diverse telephone kinds and different regulators of neuronal functionality. the main target of this quantity is to check those issues with a view to spotlight adjustments of chemokine body structure which may give a contribution to neuroAIDS and different neuropathologies.

This booklet may be of curiosity to neuroscientists, neurologists, virologists, pharmacologists, and scholars in those fields.

About the Editor:

Olimpia Meucci, MD, PhD is a Professor of Pharmacology and body structure & Microbiology and Immunology at Drexel college collage of medication in Philadelphia, PA. considering that her seminal discovery concerning the legislation of neuronal signaling through chemokines, her examine has essentially enthusiastic about the physio-pathological roles of this crucial category of neuroimmune modulators within the vital anxious approach and their involvement in neuroAIDS. those stories have considerably contributed to present figuring out of the mobile and molecular mechanisms of HIV-related neuropathology together with the interplay of the chemokine approach with drug of abuse, specifically opiates, which is still an immense quarter of research within the Meucci lab.

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