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By Robert A. Good (auth.), Professor, Dr. G. Roberto Burgio, Professor, Dr. Lars Åke Hanson, Professor, Dr. Alberto G. Ugazio (eds.

Over the previous few years, many new observations have profoundly replaced our strategies of the immune competence of the child. For the immune process, as for different platforms and capabilities, the neonatal age represents an important transition interval. actually the immune features of the fetus are inclined to outcome fro- or be conditioned by means of - a number of usually contradictory physiological necessities. at the one hand, it can definitely be a bonus for the fetus to procure an entire immunocompetence once attainable as a way to manage to do something about the eventual transplacental passage of pathogenic microorganisms and doubtless additionally so one can reject maternal cells sometimes crossing the placental nd barrier. this is often truly what happens, no less than partly, throughout the 2 and Jfd month of gestation whilst the fetus starts off to obtain his organic individuality and even as the function of a "biological ego" due to the reach­ ment via the immune procedure of the potential to discriminate among self and nonself.

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