Peptides are one of the such a lot flexible bioactive molecules, but the don't make sturdy medications, simply because they're speedy degraded or converted within the body.
to beat this challenge, solid and even as biologically energetic pseudo-peptides were built. those novel compounds open up new views in drug layout by means of offering a whole variety of hugely particular and non-toxic pharmaceuticals.
this can be the 1st paintings dedicated to the subject and attracts jointly wisdom received on varieties of peptidomimetics and different pseudo-peptides with drug houses. As such, it comprises peptoids, beta-peptides, polyamide DNA binders in addition to peptide nucleic acids.
The specialist authors and editor speak about chemical homes and balance, organic job and reactivity, in addition to functional elements of synthesis, making this a chief source for drug builders and bioorganic chemists operating with those compounds.
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